Seven years ago the Control Freaks made the decision to begin manufacturing Vitamin D Controls. It was an easy decision to make, but they decided to make it with a human serum matrix, not such an easy decision since it was a gamble. That’s because at the time, the variability in reference methods (EIA, RIA, HPLC, LC/MS) and the controversy surrounding which method was best for measuring 25-Hydroxyvitamin D (25-OH-D), the accepted marker for Vitamin D nutritional status.
It would have been much easier to use stripped serum, “human based” serum, or human serum fortified with animal serum. However, the Control Freaks simply could not, in good conscience, and did not sacrifice the quality of UTAK’s products with these inferior matrix choices. It could affect a patient’s quality of life.
They first needed to accurately measure the endogenous levels of 25-OH-D to establish a baseline response for each human serum pool used during manufacturing. Next, they needed to accurately spike-in additional amounts of 25-OH-D to achieve clinically relevant reference values, not exactly easy. Finally, the reference values had to be verified by HPLC and “standardized” so that the control could be utilized with any analytical technique.
So after two more years of research and development, UTAK is now proud to be recognized as the undeniable world leader in serum Vitamin D Controls. The assays for measuring 25-OH-D in serum are still not standardized and there is still controversy about which reference method is the “gold standard”.
There is no controversy surrounding UTAK Vitamin D Controls, however. Their proprietary manufacturing process coupled with an unwavering commitment to quality has enabled them to set the standard for all Vitamin D Controls.
View our Vitamin D Controls Website.
UTAK 100% REAL Human Serum Vitamin D Controls
